- Open jobs
- 558
- Agencies hiring
- 5
- Median pay in listings
- $49.86/hour
- Pay range
- $28.40 – $80.05/hour
- Median wage in South Carolina (BLS)
- $39.60/hour
RN - Cath Lab
RN - M/S Tele
RN - M/S Tele
RN - M/S Tele
RN - M/S Tele
RN - M/S Tele
RN - Clinic
RN - ER
RN - M/S Tele
RN - M/S Tele
Surgical Tech - CVOR
RN - PCU
RN - Tele
RN - M/S Tele
RN - Med-Surg
RN - Med-Surg
RN - Med-Surg
RN - Med-Surg
RN - Med-Surg
RN - LTAC
RN - Tele
RN - Tele
RN - LTAC
RN - Tele
RN - PCU
RN - Tele
RN - OR
RN - LTAC
RN - Radiology
RN - M/S Tele
Registered Nurse (RN) pay in South Carolina
The median wage for Registered Nurse (RN) jobs in South Carolina is $39.60 per hour ($82,368 a year full-time). Jobs on this page pay a median of $49.86/hour, from $28.40 to $80.05. Travel and contract jobs often pay more than staff positions because they include housing and meal stipends.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025. Pay in listings is converted to an hourly rate assuming 36–40 hours a week.
License and requirements
You need an active nursing license that is valid in South Carolina. South Carolina is a Nurse Licensure Compact state: if your primary state of residence is also a compact state, your multistate license lets you work here without a new license. Check the latest status at nursecompact.com before you accept an offer.
Agencies hiring for Registered Nurse (RN) jobs in South Carolina
| Agency | Open jobs | Median pay |
|---|---|---|
| AHS Staffing | 182 | $53.55/hr |
| Atlas MedStaff | 130 | $47.97/hr |
| Health Advocates Network | 109 | $50.70/hr |
| Care Team Solutions | 105 | $47.20/hr |
| GHR Healthcare | 32 | $49.31/hr |
Cities with the most Registered Nurse (RN) jobs
Charleston (143), Columbia (77), Florence (70), Orangeburg (55), North Charleston (29), Greenville (21), Seneca (20), Clinton (16), Summerville (16), Beaufort (14), Travelers Rest (13), Aiken (11)
FAQ
How much does a Registered Nurse (RN) make in South Carolina?
The median wage for Registered Nurse (RN) jobs in South Carolina is $39.60 per hour (about $82,368 a year), according to the U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025. Registered Nurse (RN) jobs listed on ReferHire pay a median of $49.86 per hour.
How many Registered Nurse (RN) jobs are open in South Carolina?
558 Registered Nurse (RN) jobs from 5 staffing agencies are open on ReferHire right now.
What license do I need?
You need an active nursing license that is valid in South Carolina. South Carolina is a Nurse Licensure Compact state: if your primary state of residence is also a compact state, your multistate license lets you work here without a new license. Check the latest status at nursecompact.com before you accept an offer.