- Open jobs
- 228
- Agencies hiring
- 5
- Median pay in listings
- $63.67/hour
- Pay range
- $27.46 – $132/hour
- Median wage in South Dakota (BLS)
- $37.53/hour
RN - ER
RN - ER
RN - ER
RN - Med-Surg
RN - ER
Cardiac Stepdown | Registered Nurse
Registered Nurse - Outpatient - Clinic
Registered Nurse - Psychiatric
Registered Nurse - Labor & Delivery
Med/Surg | Registered Nurse
Cath Lab | Registered Nurse
OR | Perfusionist
Med/Surg | Registered Nurse
Med/Surg Tele | Registered Nurse
Office/Clinic RN in Sioux Falls, South Dakota
Psych RN in Sioux Falls, South Dakota
Registered Nurse - Cardiac Cath Lab
Registered Nurse - Emergency Room
Registered Nurse - Case Management
Registered Nurse - Operating Room
Registered Nurse - Pediatric
Registered Nurse - Pediatric
Registered Nurse - Pediatric
Registered Nurse - Med - Surg
L&D RN in Rapid City, South Dakota
Med/Surg | Registered Nurse
Peds RN in Sioux Falls, South Dakota
Peds RN in Sioux Falls, South Dakota
Peds RN in Mitchell, South Dakota
Case Manager RN in Rapid City, South Dakota
Registered Nurse (RN) pay in South Dakota
The median wage for Registered Nurse (RN) jobs in South Dakota is $37.53 per hour ($78,062 a year full-time). Jobs on this page pay a median of $63.67/hour, from $27.46 to $132. Travel and contract jobs often pay more than staff positions because they include housing and meal stipends.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025. Pay in listings is converted to an hourly rate assuming 36–40 hours a week.
License and requirements
You need an active nursing license that is valid in South Dakota. South Dakota is a Nurse Licensure Compact state: if your primary state of residence is also a compact state, your multistate license lets you work here without a new license. Check the latest status at nursecompact.com before you accept an offer.
Agencies hiring for Registered Nurse (RN) jobs in South Dakota
| Agency | Open jobs | Median pay |
|---|---|---|
| AHS Staffing | 122 | $65.26/hr |
| Atlas MedStaff | 84 | $62.31/hr |
| GHR Healthcare | 15 | $62.78/hr |
| Health Advocates Network | 6 | — |
| Care Team Solutions | 1 | $47.20/hr |
Cities with the most Registered Nurse (RN) jobs
Rapid City (115), Sioux Falls (67), Aberdeen (13), Mitchell (9), Spearfish (5), Hot Springs (4), Webster (3), Flandreau (3), Yankton (2), Parkston (2), Tyndall (2), Garretson (2)
FAQ
How much does a Registered Nurse (RN) make in South Dakota?
The median wage for Registered Nurse (RN) jobs in South Dakota is $37.53 per hour (about $78,062 a year), according to the U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025. Registered Nurse (RN) jobs listed on ReferHire pay a median of $63.67 per hour.
How many Registered Nurse (RN) jobs are open in South Dakota?
228 Registered Nurse (RN) jobs from 5 staffing agencies are open on ReferHire right now.
What license do I need?
You need an active nursing license that is valid in South Dakota. South Dakota is a Nurse Licensure Compact state: if your primary state of residence is also a compact state, your multistate license lets you work here without a new license. Check the latest status at nursecompact.com before you accept an offer.